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Science has shown that the Kambo secretion has a unique and complex blend of Bioactive Peptides.


Due to the beneficial nature of these peptides, there is currently over 70 patents being lodged by scientists and pharmaceutical companies in hopes that they can replicate the benefits of Kambo.


Current Research Articles on Peptides Found in Kambo


Antimicrobial peptides from Phyllomedusa frogs: from biomolecular diversity to potential nanotechnologic medical applications

– Compilation of data on the antimicrobial, neuroactive and smooth muscle activity of Kambo peptides

Antitumor and angiostatic activities of the antimicrobial peptide Dermaseptin B2

– Promising data on the cancer-fighting potential of Kambo’s Dermaseptine B2 peptide

Dermorphin-related peptides from the skin of Phyllomedusa Bicolor

– Statistics on Dermorphin’s ability to bind with pain-relieving receptors in the brain

Deltorphins: A family of naturally occurring peptides with high affinity and selectivity for 6 opioid binding sites

– A study of Deltorphin and its ability to bind with pain-relieving receptors

Pharmacological data on Phyllokinin

– Information on Kambo’s Phyllokinin peptide and its benefits to blood pressure

Kambô, The Spirit of the Shaman

– A great write-up on the history and uses of Kambo

KAMBO: Nature’s Vaccine for the Mind and Body –

– An interview with IAKP founder Karen Kanya Darke



So what is a peptide? 

A peptide is a short chain of amino acids that when bonded perform specific functions in the human body. Insulin, Oxytocin, Growth hormone, Antibiotics, and Enzymes are all examples of peptides in our bodies. Peptides have a direct effect on mood, energy, cognitive reasoning, blood sugar, digestion, blood pressure, and immune system regulation. They can help with inflammation and even stop the growth of microorganisms in the body.



What makes Kambo peptides special? 

Kambo contains Bioactive Peptides which means they perform a specific and beneficial function in the human body. Most importantly, the peptides in Kambo are completely natural so the body recognizes them and unlocks cells to the benefits of the medicine, essentially, the human body recognizes Kambo as a natural part of its own system, which enables Kambo to cross the blood/brain barrier within the body.  This is not true for pharmaceutical drugs which often have to break into cells – generally leaving behind a residue and causing some stress in the body.  


Kambo is a natural substance that the human body recognizes, so it’s receptive to the medicine with no stress to the cells. Kambo even helps clean out the residue left by drugs.  Despite inaccurate reporting, Kambo is not toxic or poisonous to the human body. 



What are the Peptides in Kambo? 

There are 11 well-known peptides that have been isolated in Kambo secretion (Kambo contains dozens of other peptides that have still yet to be identified). This blending of various peptides is completely unique to the frog medicine. Listed below are the various peptides that have been researched and identified in Kambo:


Phyllocaerulein – a neuropeptide (a special type of peptide that helps neurons communicate in the brain) that reduces blood pressure, modifies satiety (stomach fullness) and manages sedation and thermoregulation. It’s also a potent pain killer.


Phyllokinin – a peptide that reduces blood pressure over the long-term and crosses the blood-brain barrier to help take Kambo’s benefits to the brain.


Phyllomedusin – a neuropeptide (unique to Kambo) that acts as a powerful vasodilator, widening and relaxing blood vessels, veins, and arteries.


Dermorphin – a peptide chain that acts on opioid receptors to reduce pain. It is 30-40 times more potent than morphine.


Deltorphin – another peptide that interacts with opioid receptors, showing higher selectivity for these receptors versus any compound known to man. There are 2 Deltorphins in Kambo, adding to its pain-killing properties.


Dermaseptin – a peptide with potent antimicrobial effects against bacteria, yeast, fungi, protozoa, and even enveloped viruses.


Adenoregulin – a peptide that has been shown to be highly effective in killing cancer cells, effectively turning off their fuel supply.

Tryptophyllin – a peptide that been shown to be highly potent against the yeast Candida Albicans.


Phyllolitorin, [Leu8], Rohdei, Litorin – 3 neuropeptides that stimulate gastric acid secretion and smooth muscle contraction.


From this list, you can see why Kambo has been so effective to many people looking to manage illness and pain and why its ability to heal the body differs from any modern day prescription medicine or treatment. 



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